CURRENT MEMBERS
Yan Sun, PhD
Yan Sun, PhD
Research Associate since March, 2018
Research Associate since March, 2018
Previously Postdoctoral Researcher (2013-2018)
Previously Postdoctoral Researcher (2013-2018)
Ph.D. in Pathobiology from the University of Illinois Urbana-Champaign
Ph.D. in Pathobiology from the University of Illinois Urbana-Champaign
Publications
1. Mercado-López M, Cotter CR, Kim WK, Muñoz L, Sun Y, Tapia K, and López CB. (2013) Highly Immunostimulatory RNA Derived from a Sendai Virus Defective Viral Genome. Vaccine. 2013 Oct 4. pii: S0264-410X(13)01294-2. doi: 10.1016/j.vaccine.2013.09.040. [Epub ahead of print] PMID: 2409987. PubMed link.2. Tapia K, Kim WK, Sun Y, Mercado-López X, Dunay E, Wise M, Adu M, and López CB. (2013) Defective Viral Genomes Arising In Vivo Provide Critical Danger Signals for the Triggering of Lung Antiviral Immunity. PLOS Pathogens 9(10): e1003703. doi:10.1371/journal.ppat.1003703. * Featured Article. *Co-first authors. PubMed link3. Sun Y, Jain D, Koziol-White CJ, Genoyer E, Gilbert M, Tapia K, Panettieri RA, Hodinka RL, and López CB. (2015) Immunostimulatory Defective Viral Genomes Promote Strong Innate Antiviral Responses During Respiratory Syncytial Virus Infection in Mice and Humans. PLOS Pathogens. 11(9): e1005122. doi:10.1371/journal.ppat.1005122 PubMed link4. Sun Y and López CB. (2016) Preparation of respiratory syncytial virus stocks and purification of defective viral particles. Bio-protocol 6(10): e1820. http://www.bio-protocol.org/e1820. 5. Sun Y and López CB. (2016) Respiratory syncytial virus infection in mice and detection of viral genomes in the lung using RT-qPCR. Bio-protocol 6(10): e1819. http://www.bio-protocol.org/e1819.6. Sun Y and López CB. (2016) The innate immune response to RSV: Advances in our understanding of critical viral and host factors (Review). Vaccine http://dx.doi.org/10.1016/j.vaccine.2016.09.030 7. Muallem G, Wagage S, Sun Y, DeLong JH, Valenzuela A, Harms Pritchard G, Christian, DA, Fang, Q, Buza E, Jain D, Elloso MM, López CB#, and Hunter CA#. (2017) IL-27 Limits Type 2 Immunopathology Following Parainfluenza Virus Infection. PLOS Pathogens 13(1):e1006173. doi: 10.1371/journal.ppat.1006173. #Senior authors. Publication link.8. Kenny A, Dowdle JA, Bozzacco L, McMichael TM, St. Gelais C, Panfil AR, Sun Y, Anderson MZ, Green PL, López CB, Rosenberg BR, Wu L, and Yount JS. Human Genetic Determinants of Viral Diseases (2017) (Review), Annual Reviews of Genetics. doi/abs/10.1146/annurev-genet-120116-023425. Publication link9. Xu J,* Sun Y*, Li Y, Ruthel G, Weiss SR, Raj, A, Beiting D and López CB. (2017) Replication Defective Viral Genomes Exploit A Cellular Pro-Survival Mechanism To Establish Paramyxovirus Persistence. [Preprint: BioRxiv, doi: https://doi.org/10.1101/120766]. Nature Communications Oct 6;8(1):799. doi: 10.1038/s41467-017-00909-6. Publication link.10. Sun Y, Kim EJ, Felt SA, Taylor LJ, Agarwal D, Grant GR, and López CB. (2019) A specific sequence in the genome of respiratory syncytial virus regulates the generation of copy-back defective viral genomes [Preprint: https://www.biorxiv.org/content/early/2018/06/16/349001]. PloS Pathogens, 15(4): e1007707. https://doi.org/10.1371/journal.ppat.1007707. Publications
Emmanuelle Genoyer
Emmanuelle Genoyer
Graduate Student, joined the lab in June of 2015
Graduate Student, joined the lab in June of 2015
MVP Program, Cell & Molecular Biology Graduate Group
MVP Program, Cell & Molecular Biology Graduate Group
Publications:
1. Sun Y, Jain D, Koziol-White CJ, Genoyer E, Gilbert M, Tapia K, Panettieri RA, Hodinka RL, and López CB. (2015) Immunostimulatory Defective Viral Genomes Promote Strong Innate Antiviral Responses During Respiratory Syncytial Virus Infection in Mice and Humans. PLOS Pathogens. 11(9): e1005122. doi:10.1371/journal.ppat.1005122 PubMed link2. Genoyer E and López CB (2019) Distinct intracellular distribution of full-length and defective viral RNA genomes drives functional heterogeneity during infection. J. Virol. DOI: 10.1128/JVI.01579-18. Publication link3. Genoyer E and López CB. (2019) (Review) The Impact of Defective Viruses on Infection and Immunity. Annu Rev Virol. doi: 10.1146/annurev-virology-092818-015652Publications:
Devin Fisher
Devin Fisher
Graduate Student, joined the lab in June of 2016
Graduate Student, joined the lab in June of 2016
MVP Program, Cell & Molecular Biology Graduate Group
MVP Program, Cell & Molecular Biology Graduate Group
Publications:
1. Fisher DG, Coppock GM, and López CB (2018) Virus-derived immunostimulatory RNA induces type I IFN-dependent antibodies and T-cell responses during vaccination. Vaccine, 36(28):4039-4045. doi: 10.1016/j.vaccine.2018.05.100. Publication link.2. Sengupta S, Tang S, Devine J, Anderson S, Nayak S, Zhang C, Valenzuela A, Fisher D, Grant G, López CB, and FitzGerald G. (2019) Circadian control of lung inflammation in influenza infection. Nature Communications, doi.org/10.1038/s41467-019-11400-9.Publications:
Sebastien Felt, PhD
Sebastien Felt, PhD
Postdoctoral Researcher since June, 2017
Postdoctoral Researcher since June, 2017
Ph.D. in Biology, Concentration in Molecular, Cellular, and Developmental Biology Sciences from the University of North Carolina at Charlotte.
Ph.D. in Biology, Concentration in Molecular, Cellular, and Developmental Biology Sciences from the University of North Carolina at Charlotte.
Publications:
1. Sun Y, Kim EJ, Felt SA, Taylor LJ, Agarwal D, Grant GR, and López CB. (2019) A specific sequence in the genome of respiratory syncytial virus regulates the generation of copy-back defective viral genomes [Preprint: https://www.biorxiv.org/content/early/2018/06/16/349001]. PloS Pathogens, 15(4): e1007707. https://doi.org/10.1371/journal.ppat.1007707. Publications:
Lavinia Gonzalez
Lavinia Gonzalez
Graduate Student, joined the lab in June of 2018
Graduate Student, joined the lab in June of 2018
MVP Program, Cell & Molecular Biology Graduate Group
MVP Program, Cell & Molecular Biology Graduate Group
golavo@pennmedicine.upenn.edu
golavo@pennmedicine.upenn.edu
Saori Suzuki, PhD
Saori Suzuki, PhD
Postdoctoral Researcher since May 2019
Postdoctoral Researcher since May 2019
PhD. From Kyoto University in Japan. Research Fellow and Special Contract Assistant Professor at Kyoto University and Shiga University, Japan
PhD. From Kyoto University in Japan. Research Fellow and Special Contract Assistant Professor at Kyoto University and Shiga University, Japan
saorisu@vet.upenn.edu
saorisu@vet.upenn.edu
Katherine Novak
Katherine Novak
Undergrad Researcher since September 2019
Undergrad Researcher since September 2019
Vagelos LSM program, School of Arts and Sciences, UPenn
Vagelos LSM program, School of Arts and Sciences, UPenn
knovak@sas.upenn.edu
knovak@sas.upenn.edu
Current Rotation and Summer Students
Current Rotation and Summer Students
Because we are moving soon we are not currently taking rotation or summer students
Because we are moving soon we are not currently taking rotation or summer students