CURRENT MEMBERS

David Holthausen, PhD

Lab Manager since June 2020

Ph.D. in Immunology and Molecular Pathogenesis, Emory University, Atlanta.

Publications:

1. Fisher DG, Gazzo V, Holthausen D and López CB. (2022) Non-standard viral genome-derived RNA activates TLR3 and type I IFN signaling to induce cDC1-dependent CD8+ T-cell responses during vaccination in mice. https://www.biorxiv.org/content/10.1101/2022.06.09.495494v1.full. Vaccine 40: 7270-7279. https://doi.org/10.1016/j.vaccine.2022.10.052



Emna Achouri

Bioinformatician, joined September 2020

Master’s degree in Genomics, majoring in Computational Biology, Université d’Evry (France)

emna@wustl.edu

Publications:

1. Felt SA, Sun Y, Jozwik A, Para A, Habibi MS, Nickle D, Anderson L, Achouri E, Feemster K, Cardenas AM, Turi KN, Chang M, Hartert TV, Sengupta S, Chiu C, and López CB (2021). ­­­Detection of Respiratory syncytial virus defective genomes in nasal secretions is associated with distinct clinical outcomes. Nat. Microbiol., https://doi.org/10.1038/s41564-021-00882-3.2. Felt SA, Achouri E, Faber SR and López CB (2022). Accumulation of copy-back viral genomes during respiratory syncytial virus infection is preceded by diversification of the copy-back genome population followed by selection. https://www.biorxiv.org/content/10.1101/2022.05.25.493350v1

Sebastien Felt, PhD

Staff Scientist (2022 - )

Previously Postdoctoral Researcher (2017-2022)

Ph.D. in Biology, Concentration in Molecular, Cellular, and Developmental Biology Sciences from the University of North Carolina at Charlotte.

Publications:

1. Sun Y, Kim EJ, Felt SA, Taylor LJ, Agarwal D, Grant GR, and López CB. (2019) ­­­­­­­­­A specific sequence in the genome of respiratory syncytial virus regulates the generation of copy-back defective viral genomes [Preprint: https://www.biorxiv.org/content/early/2018/06/16/349001]. PloS Pathogens, 15(4): e1007707. https://doi.org/10.1371/journal.ppat.1007707. 2. Felt SA, Sun Y, Jozwik A, Para A, Habibi MS, Nickle D, Anderson L, Achouri E, Feemster K, Cardenas AM, Turi KN, Chang M, Hartert TV, Sengupta S, Chiu C, and López CB (2021). ­­­Detection of Respiratory syncytial virus defective genomes in nasal secretions is associated with distinct clinical outcomes. Nat. Microbiol., https://doi.org/10.1038/s41564-021-00882-3.3. Felt SA and López CB (2022) Harnessing defective viruses to fight infections. Med, 3 1-2 https://doi.org/10.1016/j.medj.2021.12.0064. Gonzalez Aparicio LJ, López CB and Felt SA (2022) (Review) A Virus is a Community: Diversity within Negative Sense RNA Virus Populations. MMBR, DOI: https://doi.org/10.1128/mmbr.00086-21.5. Felt SA, Achouri E, Faber SR and López CB (2022). Accumulation of copy-back viral genomes during respiratory syncytial virus infection is preceded by diversification of the copy-back genome population followed by selection. https://www.biorxiv.org/content/10.1101/2022.05.25.493350v1

Matthew Hackbart, PhD

Postdoctoral Researcher since June 2020

Ph.D. in Biomedical Sciences from Loyola University in Chicago


Munyaradzi Tambo, PhD

Postdoctoral Researcher since August 2020

Helen Hay Whitney Foundation Fellow (2022)

Ph.D. in Population Genetics from University of Namibia


Italo Araujo Castro, PhD

Postdoctoral Researcher since September 2020

Ph.D. Molecular and Cell Biology, University of Sao Pablo, Brazil.

Publications:

1.Hiller BE, Yin Y, Perng Y, Castro I, Fox LE, Locke MC, Monte KJ, López CB, Ornitz D, Lenschow DJ (2022) Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis. PLoS Pathogens, 18(6): e1010228. https://doi.org/10.1371/journal. ppat.1010228.

Daniel Rensetti, PhD

Postdoctoral Researcher since March 2021

Ph.D. in Veterinary Sciences (virology) Universidad Nacional de la Plata, Argentina

Lavinia Gonzalez

Graduate Student, joined the lab in June 2018

DBBS, Molecular Microbiology and Microbial Pathogenesis Program

Publications:

1. Gonzalez Aparicio LJ, López CB and Felt SA (2022) (Review) A Virus is a Community: Diversity within Negative Sense RNA Virus Populations. MMBR, DOI: https://doi.org/10.1128/mmbr.00086-21.

Sydney Faber

Technician, joined the lab in June 2020

Publications:

1. Felt S, Achouri E, Faber SR and López CB (2022). Accumulation of copy-back viral genomes during respiratory syncytial virus infection is preceded by diversification of the copy-back genome population followed by selection. https://www.biorxiv.org/content/10.1101/2022.05.25.493350v1

Hanaa Saleh

Visiting Researcher, joined in September 2020


Nicole Rivera-Espinal

Graduate Student, joined the lab in May 2021

NSF-GRFP Fellow (2021)

DBBS, Molecular Microbiology and Microbial Pathogenesis Program


Patrick Wang

Undergrad, joined the lab in September 2021

Washington University Scholars Program in Medicine


Yanling Yang, PhD


Postdoctoral Researcher since November 2021

PhD in Preventive Veterinary Medicine, China Agricultural University , Beijing, China


Victoria Gnazzo, PhD

Postdoctoral Researcher since September 2021

PhD in Veterinary Medicine, Universidad de Buenos Aires, Argentina

Publications:

1. Fisher DG, Gazzo V, Holthausen D and López CB. (2022) Non-standard viral genome-derived RNA activates TLR3 and type I IFN signaling to induce cDC1-dependent CD8+ T-cell responses during vaccination in mice. https://www.biorxiv.org/content/10.1101/2022.06.09.495494v1.full. Vaccine 40: 7270-7279. https://doi.org/10.1016/j.vaccine.2022.10.052

Sarah Beth (SB) Pye

Graduate Student, joined the lab in January 2022

NSF-GRFP Fellow (2021)

DBBS, Molecular Microbiology and Microbial Pathogenesis Program


Daniela Vidal

Graduate Student, joined the lab in May 2022

DBBS, Molecular Microbiology and Microbial Pathogenesis Program


Yuchen Wang

Undergrad, joined the lab in September 2022

Washington University in St. Louis


Current Rotation and Summer Students

Sydney Briner, MMMP