CURRENT MEMBERS

David Holthausen, PhD

Lab Manager since June 2020

Ph.D. in Immunology and Molecular Pathogenesis, Emory University, Atlanta.

holthausen@wustl.edu

Publications:

1. Fisher DG, Gazzo V, Holthausen D and López CB. (2022) Non-standard viral genome-derived RNA activates TLR3 and type I IFN signaling to induce cDC1-dependent CD8+ T-cell responses during vaccination in mice. https://www.biorxiv.org/content/10.1101/2022.06.09.495494v1.full. Vaccine 40: 7270-7279. https://doi.org/10.1016/j.vaccine.2022.10.052

Emna Achouri

Bioinformatician, joined September 2020

Master’s degree in Genomics, majoring in Computational Biology, Université d’Evry (France)

emna@wustl.edu

Publications:

1. Felt SA, Sun Y, Jozwik A, Para A, Habibi MS, Nickle D, Anderson L, Achouri E, Feemster K, Cardenas AM, Turi KN, Chang M, Hartert TV, Sengupta S, Chiu C, and López CB (2021). Detection of Respiratory syncytial virus defective genomes in nasal secretions is associated with distinct clinical outcomes. Nat. Microbiol., https://doi.org/10.1038/s41564-021-00882-3.2. Felt SA, Achouri E, Faber SR and López CB (2022). Accumulation of copy-back viral genomes during respiratory syncytial virus infection is preceded by diversification of the copy-back genome population followed by selection. https://www.biorxiv.org/content/10.1101/2022.05.25.493350v13. Achouri E, Felt SA, Hackbart MS and López CB. (2023) VODKA2: An accurate method to detect copy-back and deletion viral genomes from next-generation sequencing data. https://biorxiv.org/cgi/content/short/2023.05.17.541157v1

Matthew Hackbart, PhD

Postdoctoral Researcher since June 2020

Ph.D. in Biomedical Sciences from Loyola University in Chicago

hackbart@wustl.edu

Publications:

1. Achouri E, Felt SA, Hackbart MS and López CB. (2023) VODKA2: An accurate method to detect copy-back and deletion viral genomes from next-generation sequencing data. https://biorxiv.org/cgi/content/short/2023.05.17.541157v12. Gonzalez-Aparicio LJ, Yang Y, Hackbart MS, Manzoni TB, and López CB (2023) Copyback viral genomes trigger stress granule formation independent of the antiviral response to interfere with viral translation in acute and persistent infections. https://doi.org/10.1101/2023.05.17.541157.

Munyaradzi Tambo, PhD

Postdoctoral Researcher since August 2020

Helen Hay Whitney Foundation Fellow (2022)

Ph.D. in Population Genetics from University of Namibia

tambo@wustl.edu

Italo Araujo Castro, PhD

Postdoctoral Researcher since September 2020

Ph.D. Molecular and Cell Biology, University of Sao Pablo, Brazil.

italo@wustl.edu

Publications:

1.Hiller BE, Yin Y, Perng Y, Castro I, Fox LE, Locke MC, Monte KJ, López CB, Ornitz D, Lenschow DJ (2022) Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis. PLoS Pathogens, 18(6): e1010228. https://doi.org/10.1371/journal. ppat.1010228.

Daniel Rensetti, PhD

Postdoctoral Researcher since March 2021

Ph.D. in Veterinary Sciences (virology) Universidad Nacional de la Plata, Argentina

r.daniel@wustl.edu

Lavinia Gonzalez

Graduate Student, joined the lab in June 2018

DBBS, Molecular Microbiology and Microbial Pathogenesis Program

g.lavinia@wustl.edu

Publications:

1. Gonzalez Aparicio LJ, López CB and Felt SA (2022) (Review) A Virus is a Community: Diversity within Negative Sense RNA Virus Populations. MMBR, DOI: https://doi.org/10.1128/mmbr.00086-21 .2. Gonzalez-Aparicio LJ, Yang Y, Hackbart MS, Manzoni TB, and López CB (2023) Copyback viral genomes trigger stress granule formation independent of the antiviral response to interfere with viral translation in acute and persistent infections. https://doi.org/10.1101/2023.05.17.541157.

Sydney Faber

Technician, joined the lab in June 2020

Faber@wustl.edu

Publications:

1. Felt S, Achouri E, Faber SR and López CB (2022). Accumulation of copy-back viral genomes during respiratory syncytial virus infection is preceded by diversification of the copy-back genome population followed by selection. https://www.biorxiv.org/content/10.1101/2022.05.25.493350v1

Hanaa Saleh

Visiting Researcher, joined in September 2020

h.saleh@wustl.edu

Nicole Rivera-Espinal

Graduate Student, joined the lab in May 2021

NSF-GRFP Fellow (2021)

DBBS, Molecular Microbiology and Microbial Pathogenesis Program

n.rivera-espinal@wustl.edu

Patrick Wang

Undergrad, joined the lab in September 2021

Washington University Scholars Program in Medicine

p.y.wang@wustl.edu

Yanling Yang, PhD

Postdoctoral Researcher since November 2021

PhD in Preventive Veterinary Medicine, China Agricultural University, Beijing, China

yanlingy@wustl.edu

Publications:

1. Gonzalez-Aparicio LJ, Yang Y, Hackbart MS, Manzoni TB, and López CB (2023) Copyback viral genomes trigger stress granule formation independent of the antiviral response to interfere with viral translation in acute and persistent infections. https://doi.org/10.1101/2023.05.17.541157.