Went to: BioNTech SE, Mainz, Germany as Scientist Immunomodulators
Publications:
1. SunY, KimEJ, Felt SA, TaylorLJ, Agarwal D, GrantGR, and LópezCB. (2019) A specific sequence in the genome of respiratory syncytial virus regulates the generation of copy-back defective viral genomes [Preprint:https://www.biorxiv.org/content/early/2018/06/16/349001]. PloS Pathogens, 15(4): e1007707.https://doi.org/10.1371/journal.ppat.1007707. 2. Felt SA, Sun Y, Jozwik A, Para A, Habibi MS, Nickle D, Anderson L, Achouri E, Feemster K, Cardenas AM, Turi KN, Chang M, Hartert TV, Sengupta S, Chiu C, and López CB (2021). Detection of Respiratory syncytial virus defective genomes in nasal secretions is associated with distinct clinical outcomes. Nat. Microbiol.,https://doi.org/10.1038/s41564-021-00882-3.3.Felt SA and López CB (2022) Harnessing defective viruses to fight infections. Med, 3 1-2https://doi.org/10.1016/j.medj.2021.12.0064.Gonzalez Aparicio LJ, López CB and Felt SA (2022) (Review) A Virus is a Community: Diversity within Negative Sense RNA Virus Populations. MMBR,DOI: https://doi.org/10.1128/mmbr.00086-21.5. Felt SA, Achouri E, Faber SR and López CB (2022). Accumulation of copy-back viral genomes during respiratory syncytial virus infection is preceded by diversification of the copy-back genome population followed by selection.https://www.biorxiv.org/content/10.1101/2022.05.25.493350v16. Achouri E, Felt SA, Hackbart MS, Rivera-Espinal NS and López CB. (2023) VODKA2: A fast and accurate method to detect non-standard viral genomes from large RNA-seq datasetshttps://biorxiv.org/cgi/content/short/2023.05.17.541157v1. RNA. In Press.
Yan Sun, PhD (2013-2020)
Postdoctoral Researcher (2013-2018), Research Associate (2018-2020)
Went to: Assistant Professor, Department of Microbiology & Immunology, University of Rochester, NY.
Publications:
1. Mercado-López M, Cotter CR, Kim WK, Muñoz L, Sun Y, Tapia K, and López CB. (2013) Highly Immunostimulatory RNA Derived from a Sendai Virus Defective Viral Genome. Vaccine. 2013 Oct 4. pii: S0264-410X(13)01294-2. doi: 10.1016/j.vaccine.2013.09.040. [Epub ahead of print] PMID: 2409987. PubMed link.2. Tapia K, Kim WK, Sun Y, Mercado-López X, Dunay E, Wise M, Adu M, and López CB. (2013) Defective Viral Genomes Arising In Vivo Provide Critical Danger Signals for the Triggering of Lung Antiviral Immunity. PLOS Pathogens 9(10): e1003703. doi:10.1371/journal.ppat.1003703. * Featured Article. *Co-first authors. PubMed link3. Sun Y, Jain D, Koziol-White CJ, Genoyer E, Gilbert M, Tapia K, Panettieri RA, Hodinka RL, and López CB. (2015) Immunostimulatory Defective Viral Genomes Promote Strong Innate Antiviral Responses During Respiratory Syncytial Virus Infection in Mice and Humans. PLOS Pathogens. 11(9): e1005122. doi:10.1371/journal.ppat.1005122 PubMed link4. Sun Y and López CB. (2016) Preparation of respiratory syncytial virus stocks and purification of defective viral particles. Bio-protocol 6(10): e1820. http://www.bio-protocol.org/e1820. 5. Sun Y and López CB. (2016) Respiratory syncytial virus infection in mice and detection of viral genomes in the lung using RT-qPCR. Bio-protocol 6(10): e1819. http://www.bio-protocol.org/e1819.6. Sun Y and López CB. (2016) The innate immune response to RSV: Advances in our understanding of critical viral and host factors (Review). Vaccine http://dx.doi.org/10.1016/j.vaccine.2016.09.0307. Muallem G, Wagage S, Sun Y, DeLong JH, Valenzuela A, Harms Pritchard G, Christian, DA, Fang, Q, Buza E, Jain D, Elloso MM, López CB#, and Hunter CA#. (2017) IL-27 Limits Type 2 Immunopathology Following Parainfluenza Virus Infection. PLOS Pathogens 13(1):e1006173. doi: 10.1371/journal.ppat.1006173. #Senior authors. Publication link.8. KennyA, DowdleJA, BozzaccoL, McMichael TM, St. Gelais C, Panfil AR, Sun Y, Anderson MZ, Green PL, López CB, Rosenberg BR, Wu L, and Yount JS. Human Genetic Determinants of Viral Diseases (2017) (Review), Annual Reviews of Genetics. doi/abs/10.1146/annurev-genet-120116-023425. Publication link9. Xu J,* Sun Y*, Li Y, Ruthel G, Weiss SR, Raj, A, Beiting D and López CB. (2017) Replication Defective Viral Genomes Exploit A Cellular Pro-Survival Mechanism To Establish Paramyxovirus Persistence. [Preprint: BioRxiv, doi: https://doi.org/10.1101/120766]. Nature Communications Oct 6;8(1):799. doi: 10.1038/s41467-017-00909-6. Publication link.10. SunY, KimEJ, Felt SA, TaylorLJ, Agarwal D, GrantGR, and LópezCB. (2019) A specific sequence in the genome of respiratory syncytial virus regulates the generation of copy-back defective viral genomes [Preprint: https://www.biorxiv.org/content/early/2018/06/16/349001]. PloS Pathogens, 15(4): e1007707. https://doi.org/10.1371/journal.ppat.1007707. 11.Felt SA,Sun Y, Jozwik A, Para A, Habibi MS, Nickle D, Anderson L, Achouri E, Feemster K, Cardenas AM, Turi KN, Chang M, Hartert TV, Sengupta S, Chiu C, and López CB (2021). Detection of Respiratory syncytial virus defective genomes in nasal secretions is associated with distinct clinical outcomes. Nat. Microbiol., https://doi.org/10.1038/s41564-021-00882-3.
Saori Suzuki, PhD (2019)
*Saori could not move with the lab to St. Louis and she had to left us way too early!
Current position: Postdoctoral Fellow at Princeton
Jie Xu, Ph.D. (2014-2017)
Current position: Project Management Scientist / Senior Fellow. Abmart Inc-China Northwestern University Joint Research Institute. Shanghai, China.
Publications:
1. Xu J, Mercado-López X, Grier J, Kim W, Chun L, Irvine EB, Del Toro Y, Kell A, Hur S, Gale M, Raj A, and López CB. (2015) Identification of a Natural Viral RNA Motif that Facilitates Viral Recognition by RIG-I-Like Receptors. mBio 6(5):e01265-15. doi:10.1128/mBio.01265-15. PubMed link2. Xu J,* Sun Y*, Li Y, Ruthel G, Weiss SR, Raj, A, Beiting D and López CB. (2017) Replication Defective Viral Genomes Exploit A Cellular Pro-Survival Mechanism To Establish Paramyxovirus Persistence. [Preprint: BioRxiv, doi: https://doi.org/10.1101/120766]. Nature Communications Oct 6;8(1):799. doi: 10.1038/s41467-017-00909-6. Publication link.
Jennifer Grier, Ph.D. (2013-2016)
Went to: Visiting Assistant Professor of Biology, Linfield College, OR.
Current position: Clinical Assistant Professor of Immunology at University of South Carolina School of Medicine Greenville, USA
Publications:
1. Xu J, Mercado-López X, Grier J, Kim W, Chun L, Irvine EB, Del Toro Y, Kell A, Hur S, Gale M, Raj A, and López CB. (2015) Identification of a Natural Viral RNA Motif that Facilitates Viral Recognition by RIG-I-Like Receptors. mBio 6(5):e01265-15. doi:10.1128/mBio.01265-15. PubMed link2. Philip NH, DeLaney A, Peterson LW, Santos-Marerro M, Grier JT, Sun Y, Wynosky-Dolfi MA, Zwack EE, Hu B, Olson TM, Rongvaux A, Pope SD, López CB, Oberst A, Beiting DP, Henao-Mejia J, and Brodsky IE. (2016) Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death PLOS Pathogens 12(10): e1005910. doi:10.1371/ journal.ppat.1005910. Publication link.
Xiomara Mercado-López, Ph.D. (2010-2013)
Went to: Assistant Professor, Universidad de Puerto Rico, Campus Arecibo.
Currently: Post doctoral fellow, UPenn
Publications:
1. Mercado-López X, Cotter CR, Kim WK, Muñoz L, Sun Y, Tapia K, and López CB. (2013) Highly Immunostimulatory RNA Derived from a Sendai Virus Defective Viral Genome. Vaccine. 2013 Oct 4. pii: S0264-410X(13)01294-2. doi: 10.1016/j.vaccine.2013.09.040. [Epub ahead of print] PMID: 2409987. PubMed link.2. Tapia K, Kim WK, Sun Y, Mercado-López X, Dunay E, Wise M, Adu M, and López CB. (2013) Defective Viral Genomes Arising In Vivo Provide Critical Danger Signals for the Triggering of Lung Antiviral Immunity. PLOS Pathogens 9(10): e1003703. doi:10.1371/journal.ppat.1003703. * Featured Article. *Co-first authors. PubMed link3. Xu J, Mercado-López X, Grier J, Kim W, Chun L, Irvine EB, Del Toro Y, Kell A, Hur S, Gale M, Raj A, and López CB. (2015) Identification of a Natural Viral RNA Motif that Facilitates Viral Recognition by RIG-I-Like Receptors. mBio 6(5):e01265-15. doi:10.1128/mBio.01265-15. PubMed link
Maria Ines Barria, PhD (2009-2010)
Went to: Postdoctoral Fellow, Mount Sinai School of Medicine, NY
Current position: Assistant Professor University of Concepcion, Chile.
Graduate Students
Rosa Maria Mendes Viana (2023-2024)
Visiting Student/Graduate Student, joined the lab in October2023
University of Sao Paulo, Brasil
Went to: Back to Brazil to finish her PhD
Devin Fisher (2016-2020)
Position in the Lopez Lab: MVP Program, Cell & Molecular Biology Graduate Group, UPenn
Went To: Science Communications at the Vaccine Research Center, NIH
Publications:
1. Fisher DG, Coppock GM, and López CB (2018) Virus-derived immunostimulatory RNA induces type I IFN-dependent antibodies and T-cell responses during vaccination. Vaccine, 36(28):4039-4045. doi: 10.1016/j.vaccine.2018.05.100. Publication link.2. Sengupta S, Tang S, Devine J, Anderson S, Nayak S, Zhang C, Valenzuela A, Fisher D, Grant G, LópezCB, and FitzGerald G. (2019) Circadian control of lung inflammation in influenza infection. Nature Communications, doi.org/10.1038/s41467-019-11400-9. 3. Fisher DG, Gazzo V,Holthausen D and López CB. (2022) Non-standard viral genome-derived RNA activates TLR3 and type I IFN signaling to induce cDC1-dependent CD8+ T-cell responses during vaccination in mice. https://www.biorxiv.org/content/10.1101/2022.06.09.495494v1.full. In press, Vaccine.
Emmanuelle Genoyer (2015-2020)
Position in the Lopez Lab: Graduate Student, MVP Program, Cell & Molecular Biology Graduate Group, UPenn
Went to: Postdoc at the Gale Lab in the University of Washington in Seattle
Publications:
1. Sun Y, Jain D, Koziol-White CJ, Genoyer E, Gilbert M, Tapia K, Panettieri RA, Hodinka RL, and López CB. (2015) Immunostimulatory Defective Viral Genomes Promote Strong Innate Antiviral Responses During Respiratory Syncytial Virus Infection in Mice and Humans. PLOS Pathogens. 11(9): e1005122. doi:10.1371/journal.ppat.1005122 PubMed link2. Genoyer E and LópezCB (2019) Distinct intracellular distribution of full-length and defective viral RNA genomes drives functional heterogeneity during infection. J. Virol. DOI: 10.1128/JVI.01579-18. Publication link3. Genoyer E and LópezCB. (2019) (Review) The Impact of Defective Viruses on Infection and Immunity. Annu Rev Virol. doi: 10.1146/annurev-virology-092818-0156524. GenoyerE, KulejK, HungCT, ThibaultPA, AzarmK, TakimotoT, GarciaBA, LeeB, LakdawalaS, WeitzmanWD and López CB (2020). The Viral Polymerase Complex Mediates the Interaction of vRNPs with Recycling Endosomes During SeV Assembly. mBio, https://doi.org/10.1128/mBio.02028-20..
Tomaz Manzoni (2017-2019)
Position in the Lopez Lab: Graduate Student, MVP Program, Cell & Molecular Biology Graduate Group, UPenn
Went to: Continue PhD work in Paul Bates Lab @ UPenn as he could not relocate to St Louis with the Lab
Publications:
1. Manzoni TB and López CB. (2018) (Review) Defective (Interfering) Viral Genomes Re-Explored: Impact on Antiviral Immunity and Virus Persistence. Future Virology. Published online: DOI: 10.2217/fvl-2018-0021.2. García GL, Valenzuela A, Manzoni TB, Vaughan A, and LópezCB (2020) Distinct chronic post-viral lung disease upon infection with influenza or parainfluenza viruses differentially impact superinfection outcome. Am. J. Pathol. 190/3.3.Gonzalez-Aparicio LJ, Yang Y, Hackbart MS, Manzoni TB, and López CB (2023) Copyback viral genomes trigger stress granule formation independent of the antiviral response to interfere with viral translation in acute and persistent infections.https://doi.org/10.1101/2023.05.17.541157.
Jia Xue (2013-2015)
Position in the Lopez Lab: Visiting Scholar Graduate Student
Went to: finish her PhD in China
Publications:
1. Benitez AA, Panis M, Xue J, Shim JV, Varble A, Frick AL, López CB, Sachs D, and tenOever BR. (2015) In vivo RNAi screening identifies MDA5 as a contributor to the cellular defense against influenza A virus. Cell Reports, published online on 11 June, 2015doi:10.1016/j.celrep.2015.05.032. PubMed link.2. Xue J, Chambers BS, Hensley SE and López CB. (2016) Propagation and characterization of influenza virus stocks that are not loaded with defective viral genomes and hemagglutinin mutations. Front. Microbiol. 7:326 doi: 10.3389/fmicb.2016.0032. PubMed link3. Zhang T, YinC, Boyd DF, QuaratoG, IngramJP, ShubinaM, RaganKB, IshizukaT, TummersB, RodriguezD, XueJ, KaiserWJ, LópezCB, XuY, UptonJW, ThomasPG, GreenDR, and BalachandranS (2020). Influenza virus Z-RNAs induce ZBP1-mediated necroptosis. Cell 181, 1115–1129.
Won-keun Kim (2008-2013)
Position in the Lopez Lab: Graduate Student, Mount Sinai School of Medicine, NY.
Went to: Research Instructor, Korea University
Current position: Assistant Professor, Department of Microbiology, Hallym University, Korea.
Publications:
1.Cotter C, Kim WK, Nguyen M, Yount J, López CB, Blaho, and Moran TM. (2011) The Virion Host Shut-off (vhs) Protein of HSV-1 Blocks the Replication-Independent Activation of NF-κB in Dendritic Cells. J. Virol. Sept 21, EPub Ahead of Print. PMID: 2193765. PubMed link.2. Mercado-López X, Cotter CR, Kim WK, Muñoz L, Sun Y, Tapia K, and López CB. (2013) Highly Immunostimulatory RNA Derived from a Sendai Virus Defective Viral Genome. Vaccine. 2013 Oct 4. pii: S0264-410X(13)01294-2. doi: 10.1016/j.vaccine.2013.09.040. [Epub ahead of print] PMID: 2409987. PubMed link.3. Tapia K, Kim WK, Sun Y, Mercado-López X, Dunay E, Wise M, Adu M, and López CB. (2013) Defective Viral Genomes Arising In Vivo Provide Critical Danger Signals for the Triggering of Lung Antiviral Immunity. PLOS Pathogens 9(10): e1003703. doi:10.1371/journal.ppat.1003703. * Featured Article. *Co-first authors. PubMed link4. Kim WK, Jain D, Sánchez MD, Koziol-White C, Matthews K, Ge M, Haczku A, Panettieri RA, Frieman MB, and López CB. (2014) Deficiency of Melanoma Differentiation-associated protein 5 results in Exacerbated Chronic Post-Viral Lung Inflammation. Am. J. Respir. Crit. Care Med. 189(4):437-48. doi: 10.1164/rccm.201307-1338OC. PMID: 24417465. PubMed link.5. Xu J, Mercado-López X, Grier J, Kim WK, Chun L, Irvine EB, Del Toro Y, Kell A, Hur S, Gale M, Raj A, and López CB. (2015) Identification of a Natural Viral RNA Motif that Facilitates Viral Recognition by RIG-I-Like Receptors. mBio 6(5):e01265-15. doi:10.1128/mBio.01265-15. PubMed link
Tamar Hermesh (2005-2010)
Position in the Lopez Lab: Graduate Student (co-mentor), Mount Sinai School of Medicine, NY.
Went to: Postdoctoral Fellow, Rockefeller University, NY
Current: Medical Intern Hillel Yaffe Medical Center, Israel
Publications:
1. López CB, Yount JS, Hermesh T and Moran TM. (2006) Sendai Virus Infection Induces Efficient Adaptive Immunity Independently of Type I IFNs. J. Virol. 80:4538-4545. PMID: 16611914, PMCID: PMC1472017. PubMed link.2. Moltedo B, López CB, Pazos M, Becker MI, Hermesh T and Moran TM. (2009) Cutting Edge: stealth Influenza Virus Replication Precedes the Initiation of Adaptive Immunity. J. Immunol. 183:3569-3573. PMID: 19717515.PubMed link.3. Hermesh T, Moltedo B, Moran TM and López CB. (2010) Antiviral Instruction of Bone Marrow Leukocytes during Respiratory Viral Infections. Cell Host & Microbe.7:343-353. PMID: 20478536. PMCID: PMC2874206 * Featured Article and Previewed. PubMed link.4. Hermesh T, Moltedo B, López CB and Moran TM. (2010) Buying Time—The Immune System Determinants of the Incubation Period to Respiratory Viruses-Review. Viruses 2:2541-2558. PMID: 21994630 PMCID: PMC3185581. PubMed link.5. Hermesh T, Moran TM, Jain. D, and López CB. (2012) Granulocyte colony-stimulating factor protects mice during respiratory virus infections. PLOS One 7(5): e37334. doi:10.1371/journal.pone.0037334. PMID: 22615983 PMCID: PMC3353936.PubMed link.
Jacob Yount (2002-2007)
Position in the Lopez Lab: Graduate Student (co-mentor), Mount Sinai School of Medicine, NY.
Went to: Postdoctoral Fellow, Rockefeller University, NY
Current position: Associate Professor with tenure, Center for Microbial Interface Biology, Ohio State University.
Publications:
1. López CB, Yount JS and Moran TM. (2006) Minireview. TLR-independent Triggering of Dendritic Cell Maturation by Viruses. J. Virol. 80:3128-3134. PMID: 16505141, PMCID: PMC1440398. PubMed link.2. López CB, Yount JS, Hermesh T and Moran TM. (2006) Sendai Virus Infection Induces Efficient Adaptive Immunity Independently of Type I IFNs. J. Virol. 80:4538-4545. PMID: 16611914, PMCID: PMC1472017. PubMed link.3. Yount JS, Kraus T, Horvath C, Moran TM and López CB. (2006) A Novel Role for Defective Interfering Particles in Enhancing Dendritic Cell Maturation. J. Immunol. 177:4503-4513. PMID: 16982887. PubMed link.4. Yount JS, Moran TM and López CB. (2007) Cytokine-Independent Upregulation of MDA5 in Viral Infection. J. Virol. 81:7316-7319. PMID: 17475649, PMCID: PMC1933291. PubMed link.5. Yount JS, Gitlin L, Moran TM and López CB. (2008) MDA5 Participates in the Detection of Paramyxovirus Infection and is Essential for the Early Activation of DCs in Response to SeV DI Particles. J. Immunol. 180:4910-4919. PMID: 18354215. PubMed link.6. Cotter C, Kim WK, Nguyen M, Yount J, López CB, Blaho, and Moran TM. (2011) The Virion Host Shut-off (vhs) Protein of HSV-1 Blocks the Replication-Independent Activation of NF-κB in Dendritic Cells. J. Virol. Sept 21, EPub Ahead of Print. PMID: 2193765. PubMed link.
Vet Students
Ali Sanz (summer 2017)
PennVet Student
Emma Price (summer 2016, winter 2018/19)
PennVet Student
Undergrads
Patrick Wang (2021-2024)
Undergrad
Washington University Scholars Program in Medicine
Went to: Medical School at University of Chicago
Katherine Novak (2019)
Undergrad Researcher
Vagelos LSM program, School of Arts and Sciences, UPenn.
Geyon Lee Garcia (2016-2019)
Post-Bach trainee and PREP scholar, UPenn
Went to: MD/PHD program at University of Pittsburgh
Publications:
1. García GL, Valenzuela A, Manzoni T, Vaughan A, and LópezCB (2020) Distinct chronic post-viral lung disease upon infection with influenza or parainfluenza viruses differentially impact superinfection outcome. Am. J. Pathol. 190/3.
Ker-Cheng Chen (2017)
Undergraduate Student, 2017,UPenn
Position: School of Arts & Sciences, UPenn.
Christiana Shaw (2016)
Undergraduate Student, UPenn
School of Arts & Sciences, UPenn
Current Position: Investment Banking Analyst at TD Securities
Lauren Chun (2014-2016)
School of Arts & Sciences, UPenn
Went to: Research Assistant @ UCSF
Current position: MD student at UCSD
Publications:
Xu J, Mercado-López X, Grier J, Kim WK, Chun L, Irvine EB, Del Toro Y, Kell A, Hur S, Gale M, Raj A, and López CB. (2015) Identification of a Natural Viral RNA Motif that Facilitates Viral Recognition by RIG-I-Like Receptors. mBio 6(5):e01265-15. doi:10.1128/mBio.01265-15. PubMed link
Derek Standlee (2014-2016)
School of Arts & Sciences, UPenn
Went to: Vet School at Tufts.
Micah Gilbert (2013-2015)
School of Arts & Sciences, UPenn
Publications:
Sun Y, Jain D, Koziol-White CJ, Genoyer E, Gilbert M, Tapia K, Panettieri RA, Hodinka RL, and López CB. (2015) Immunostimulatory Defective Viral Genomes Promote Strong Innate Antiviral Responses During Respiratory Syncytial Virus Infection in Mice and Humans. PLOS Pathogens. 11(9): e1005122. doi:10.1371/journal.ppat.1005122 PubMed link
Emily Dunay (2011-2015)
School of Arts & Sciences, UPenn
Went to: Vet School University of Pennsylvania School of Veterinary Medicine.
Publications:
Tapia K, Kim WK, Sun Y, Mercado-López X, Dunay E, Wise M, Adu M, and López CB. (2013) Defective Viral Genomes Arising In Vivo Provide Critical Danger Signals for the Triggering of Lung Antiviral Immunity. PLOS Pathogens 9(10): e1003703. doi:10.1371/journal.ppat.1003703. * Featured Article. *Co-first authors. PubMed link
Lakshmi Bhagavathula (2012-2013)
UPenn, Master in Biotechnology
Went to: Research Specialist Penn Gene Targeting Core
Next position: Graduate Student (PhD) at Rutgers University, NJ.
Olga Herrera (2009-2010)
PREP Student, Mount Sinai School of Medicine, NY.
Went to: continued PREP program at Mount Sinai, NY.
Current position: Research Associate at Regeneron, NY.
Lab Managers, Research Assistants, Technicians
David Holthausen, PhD (2020-2023)
Position: Lab Manager
Went to: Research Microbiologist at USDA, ARS, RIDU
Went to: Graduate Student at Saint Louis University
Publications:
GnazzoV, SalehH, Castro I, Boon AJ, Brien J and López CB (2024) DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge[preprint: bioRxiv 2024.10.27.620508v1]. Submitted.
Alex Valenzuela (2015-2017)
Position: Research Specialists A
Went to: Post bach at UCSF
Current: MD student at UCLA
Publications:
1. Muallem G, Wagage S, Sun Y, DeLong JH, Valenzuela A, Harms Pritchard G, Christian, DA, Fang, Q, Buza E, Jain D, Elloso MM, López CB#, and Hunter CA#. (2017) IL-27 Limits Type 2 Immunopathology Following Parainfluenza Virus Infection. PLOS Pathogens 13(1):e1006173. doi: 10.1371/journal.ppat.1006173. #Senior authors. Publication link.2.Sengupta S, Tang S, Devine J, Anderson S, Nayak S, Zhang C, Valenzuela A, Fisher D, Grant G, López CB, and FitzGerald G. (2019) Circadian control of lung inflammation in influenza infection. Nature Communications, doi.org/10.1038/s41467-019-11400-9.3. García GL, Valenzuela A, Manzoni T, Vaughan A, and LópezCB (2020) Distinct chronic post-viral lung disease upon infection with influenza or parainfluenza viruses differentially impact superinfection outcome. Am. J. Pathol. 190/3.
Deepika Jain, Ph.D (2011-2014)
Position: Research Specialist D / Lab Manager.
Went to: Eurofins Group, PA
Current Position: Analytical and Quality Control Scientist/Manager at Eurofins Group, PA
Publications:
1. Hermesh T, Moran TM, Jain. D, and López CB. (2012) Granulocyte colony-stimulating factor protects mice during respiratory virus infections. PLOS One 7(5): e37334. doi:10.1371/journal.pone.0037334. PMID: 22615983 PMCID: PMC3353936.PubMed link.2. Kim WK, Jain D, Sánchez MD, Koziol-White C, Matthews K, Ge M, Haczku A, Panettieri RA, Frieman MB, and López CB. (2014) Deficiency of Melanoma Differentiation-associated protein 5 results in Exacerbated Chronic Post-Viral Lung Inflammation. Am. J. Respir. Crit. Care Med. 189(4):437-48. doi: 10.1164/rccm.201307-1338OC. PMID: 24417465. PubMed link.3. Sun Y, Jain D, Koziol-White CJ, Genoyer E, Gilbert M, Tapia K, Panettieri RA, Hodinka RL, and López CB. (2015) Immunostimulatory Defective Viral Genomes Promote Strong Innate Antiviral Responses During Respiratory Syncytial Virus Infection in Mice and Humans. PLOS Pathogens. 11(9): e1005122. doi:10.1371/journal.ppat.1005122 PubMed link
Karla Tapia (2008-2012)
Position: Research Specialist C
Went to: Research Technician, Universidad Católica de Chile.
Current Position: Microbiology Analyst, Sema Lab, Chile.
Publications:
1.Neil RC, Tapia KA, Dandapani A, MacArthur BD, López C, Ma’ayan A. (2011). Stochastic model of virus and defective interfering particle spread across mammalian cells with immune response. Q-bio.PE, arXiv:1108.4901. Publication link.2. Mercado-López X, Cotter CR, Kim WK, Muñoz L, Sun Y, Tapia K, and López CB. (2013) Highly Immunostimulatory RNA Derived from a Sendai Virus Defective Viral Genome. Vaccine. 2013 Oct 4. pii: S0264-410X(13)01294-2. doi: 10.1016/j.vaccine.2013.09.040. [Epub ahead of print] PMID: 2409987. PubMed link.3. Tapia K, Kim WK, Sun Y, Mercado-López X, Dunay E, Wise M, Adu M, and López CB. (2013) Defective Viral Genomes Arising In Vivo Provide Critical Danger Signals for the Triggering of Lung Antiviral Immunity. PLOS Pathogens 9(10): e1003703. doi:10.1371/journal.ppat.1003703. * Featured Article. *Co-first authors. PubMed link4. Sun Y, Jain D, Koziol-White CJ, Genoyer E, Gilbert M, Tapia K, Panettieri RA, Hodinka RL, and López CB. (2015) Immunostimulatory Defective Viral Genomes Promote Strong Innate Antiviral Responses During Respiratory Syncytial Virus Infection in Mice and Humans. PLOS Pathogens. 11(9): e1005122. doi:10.1371/journal.ppat.1005122 PubMed link
Luis Muñoz (2003-2011)
Position: Research Specialist D, Lab manager
Went to: ImClone, NY
Publications:
Mercado-López X, Cotter CR, Kim WK, Muñoz L, Sun Y, Tapia K, and López CB. (2013) Highly Immunostimulatory RNA Derived from a Sendai Virus Defective Viral Genome. Vaccine. 2013 Oct 4. pii: S0264-410X(13)01294-2. doi: 10.1016/j.vaccine.2013.09.040. [Epub ahead of print] PMID: 2409987. PubMed link.